Mass Effect has two leads, Mark Meer and Jennifer Hale, but you’ll only hear one of them as Commander Shepard per playthrough. According to player stats, most people play as a guy, meaning Mark Meer is their Shepard throughout the trilogy.
However, Meer encourages players to give FemShep a go - purely so they can enjoy the performance of his co-star, Hale. Speaking with PC Gamer, Meer says that he’s a huge fan of her work, and doesn’t have any problem with players choosing to only play as FemShep because of her performance.
I usually play as FemShep, but when I do play BroShep, he’s usually a Paragon, because dude just sounds like a Goodie Two Shoes Boy Scout. Plus Renegade BroShep gave off serious roid rage vibes to me in a way Renegade FemShep didn’t.